HepCnet Logo, Hepatitis C information and support, hep c information, hepatitis c message boards chat support and informationHepatitis C resources and support hepcnet, abigsam and lyric hepatitis c information and support Make a Donation »  
 
Main Page | About HepCnet | Contact Info
Hepatitis C
F.A.Q.
Viral Hepatitis C - Frequently Asked Questions
Nutrition & Hep C
Nutrition and Diet Recommendations for people with Chronic Hepatitis C
Nutrition & Cirrhosis
Nutrition information for people with Cirrhosis
Drugs & Liver Damage
Drugs that may cause liver dysfunction or damage
Hepatitis C Tests
Serologic Tests Used to Diagnose Hepatitis C
Scoring/Staging Hepatitis C & Cirrhosis
Scoring Systems for Staging of Chronic Hepatitis and Cirrhosis
Message Boards
Open Discussion
Treatments & Studies
Heppo Friends & Fun
HepCnet Chat
aBigSam and Lyric's
Hep C Support Chat
Member Stories
Read members stories about how Hepatitis C has affected their lives

Photo Album

Pictures of some of our members
Artistic Expressions
Various forms of art submitted by our members
News & Info
Heppo Fest information and other News
Heppo
Recipe Exchange
Recipes submitted by HepCnet members
Sign Guestbook
View Guestbook
Make an entry to our Guestbook and let us know that you were here!
Related Links
Other sites that offer information and support about Hepatitis C
Link to Us!
How to Link your Web Site to HepCnet
Web Rings & Awards
Web rings that HepCnet has joined and awards received
The Hep C Stuff Archive
The official repository for every member of HepCnet to store info and links
Top    Back

Drugs and Liver Damage or Dysfunction
DRUGS THAT MAY CAUSE LIVER DYSFUNCTION OR DAMAGE

The liver is the principal organ that is capable of converting drugs into forms that can be readily eliminated from the body. Given the diversity in use today and the complex burden they impose upon the liver, it is not surprising that a broad spectrum of adverse drug's effects on liver functions and structures has been documented. The reactions range from mild and transient changes in the results of liver function tests to complete liver failure with death of the host. Many drugs may affect the liver adversely in more than one way, as cited below in several listings. The use of the following drugs requires careful monitoring of their effects on the liver during the entire course of treatment.

This list is just a general guideline. Many drugs affect the liver to one degree or another and we can't list all of them here; new drugs are always being approved for general use. Read the accompanying literature with your prescriptions and always consult with your doctor or pharmacist about any new medication if you have liver disease!

Drugs that may cause ACUTE DOSE-DEPENDENT LIVER DAMAGE
(resembling acute viral hepatitis)

  • acetaminophen
  • salicylates (doses over 2 grams daily)

Drugs that may cause ACUTE DOSE-INDEPENDENT LIVER DAMAGE
(resembling acute viral hepatitis)

  • acebutolol
  • indomethacin
  • phenylbutazone
  • allopurinol
  • isoniazid
  • phenytoin
  • atenolol
  • ketoconazole
  • piroxicam
  • carbamazepine
  • labetalol
  • probenecid
  • cimetidine
  • maprotiline
  • pyrazinamide
  • dantrolene
  • metoprolol
  • quinidine
  • diclofenac
  • mianserin
  • quinine
  • diltiazem
  • naproxen
  • ranitidine
  • enflurane
  • para-aminosalicylic acid
  • sulfonamides
  • ethambutol
  • penicillins
  • sulindac
  • ethionamide
  • phenelzine
  • tricyclic antidepressants
  • halothane
  • phenindione
  • valproic acid
  • ibuprofen
  • phenobarbital
  • verapamil
  • Drugs that may cause ACUTE FATTY INFILTRATION OF THE LIVER
  • adrenocortical steroids
  • phenothiazines
  • sulfonamides
  • antithyroid drugs
  • phenytoin
  • tetracyclines
  • isoniazid
  • salicylates
  • valproic acid
  • methotrexate
  • Drugs that may cause CHOLESTATIC JAUNDICE
  • actinomycin D
  • chlorpropamide
  • erythromycin
  • amoxicillin/clavulanate
  • cloxacillin flecainide
  • azathioprine
  • cyclophosphamide
  • flurazepam
  • captopril
  • cyclosporine
  • flutamide
  • carbamazepine
  • danazol
  • glyburide
  • carbimazole
  • diazepam
  • gold
  • cephalosporins
  • disopyramide
  • griseofulvin
  • chlordiazepoxide
  • enalapril
  • enalapril
  • haloperidol
  • ketoconazole
  • norethandrolone
  • sulfonamides
  • mercaptopurine
  • oral contraceptives
  • tamoxifen
  • methyltestosterone
  • oxacillin
  • thiabendazole
  • nifedipine
  • penicillamine
  • tolbutamide
  • nitrofurantoin
  • phenothiazines
  • tricyclic antidepressants
  • nonsteroidal
  • phenytoin troleandomycin
  • anti-inflammatory drugs
  • propoxyphene
  • verapamil
  • Drugs that may cause LIVER GRANULOMAS (chronic inflammatory nodules)
  • allopurinol
  • gold
  • phenytoin
  • aspirin
  • hydralazine
  • procainamide
  • carbamazepine
  • isoniazid
  • quinidine
  • chlorpromazine
  • isoniazid
  • quinidine
  • chlorpromazine
  • nitrofurantoin
  • sulfonamides
  • diltiazem
  • penicillin
  • tolbutamide
  • disopyramide
  • phenylbutazone
  • Drugs that may cause CHRONIC LIVER DISEASE

    Drugs that may cause active chronic hepatitis

    • acetaminophen (chronic use, large doses)
    • dantrolene
    • methyldopa
    • isoniazid
    • nitrofurantoin

    Drugs that may cause liver cirrhosis or fibrosis (scarring)

    • methotrexate
    • terbinafine HCI (Lamisil, Sporanox)
    • nicotinic acid

    Drugs that may cause chronic cholestasis (resembling primary biliary cirrhosis)

    • chlorpromazine/valproic acid (combination)
    • imipramine
    • thiabendazole
    • phenothiazines
    • tolbutamide
    • chlorpropamide/erythro-mycin (combination)
    • phenytoin

    Drugs that may cause LIVER TUMORS (benign and malignant)

    • anabolic steroids
    • oral contraceptives
    • thorotrast
    • danazol
    • testosterone

    Drugs that may cause DAMAGE TO LIVER BLOOD VESSELS

    • adriamycin
    • dacarbazine
    • thioquanine
    • anabolic steroids
    • mercaptopurine
    • vincristine
    • azathioprine
    • methotrexate
    • vitamin A (excessive doses)
    • carmustine
    • mitomycin
    • cyclophosphamide/cyclo-sporine (combination)
    • oral contraceptives

     

        Page last updated: March 7, 2003


    Home  |  About HepCnet  |  Contact Information
    Hep C FAQ  |  Nutrition & Hep C |  Nutrition & Cirrhosis
    Drugs & Liver Damage  |  Hep C Tests  | Scoring/Staging Hepatitis C & Cirrhosis
    HepCnet Message Boards  |  HepCnet Chat  |  Artistic Expressions  |  Member Stories  
    Photo Album  |  News & Info  |  Heppo Recipe Exchange  |  Sign Guestbook  |  View Guestbook
    The Hep C Stuff Archives  |  Related Links  |  Web Rings & Awards  |  Link to HepCnet!

    Copyright 2000, 2001, 2002. 2003 HepCnet.net. All rights reserved

    Site Design by Wolf Web Publications.