Drugs That May Cause Liver Dysfunction Or Damage – And How The Lost Book of Remedies Can Help
Lyric and Wyck’s Hepatitis C Story and The Lost Book Remedies
August Hepatitis Fest in Bennett Spring State Park in Missouri (The Lost Book of Remedies Opening)

Drugs That May Cause Liver Dysfunction Or Damage – And How The Lost Book of Remedies Can Help

Drugs that may cause liver damage

The liver is the principal organ that is capable of converting drugs into forms that can be readily eliminated from the body.

Given the diversity in use today and the complex burden they impose upon the liver, it is not surprising that a broad spectrum of adverse drug’s effects on liver functions and structures has been documented.

The reactions range from mild and transient changes in the results of liver function tests to complete liver failure with death of the host. Many drugs may affect the liver adversely in more than one way, as cited below in several listings.

The use of the following drugs requires careful monitoring of their effects on the liver during the entire course of treatment and the new lost book of herbal remedies can help a ton in fixing this by providing herbs that can remedy the situation.

This list is just a general guideline. Many drugs affect the liver to one degree or another and we can’t list all of them here; new drugs are always being approved for general use.

Read the accompanying literature with your prescriptions and always consult with your doctor or pharmacist about any new medication if you have liver disease!

Drugs that may cause ACUTE DOSE-DEPENDENT LIVER DAMAGE
(resembling acute viral hepatitis)

  • acetaminophen
  • salicylates (doses over 2 grams daily)

Drugs that may cause ACUTE DOSE-INDEPENDENT LIVER DAMAGE
(resembling acute viral hepatitis)

Drugs that may cause ACUTE DOSE-INDEPENDENT LIVER DAMAGE
(resembling acute viral hepatitis)

  • acebutolol
  • indomethacin
  • phenylbutazone
  • allopurinol
  • isoniazid
  • phenytoin
  • atenolol
  • ketoconazole
  • piroxicam
  • carbamazepine
  • labetalol
  • probenecid
  • cimetidine
  • maprotiline
  • pyrazinamide
  • dantrolene
  • metoprolol
  • quinidine
  • diclofenac
  • mianserin
  • quinine
  • diltiazem
  • naproxen
  • ranitidine
  • enflurane
  • para-aminosalicylic acid
  • sulfonamides
  • ethambutol
  • penicillins
  • sulindac
  • ethionamide
  • phenelzine
  • tricyclic antidepressants
  • halothane
  • phenindione
  • valproic acid
  • ibuprofen
  • phenobarbital
  • verapamil

Drugs that may cause ACUTE FATTY INFILTRATION OF THE LIVER

  • adrenocortical steroids
  • phenothiazines
  • sulfonamides
  • antithyroid drugs
  • phenytoin
  • tetracyclines
  • isoniazid
  • salicylates
  • valproic acid
  • methotrexate

Drugs that may cause CHOLESTATIC JAUNDICE

  • actinomycin D
  • chlorpropamide
  • erythromycin
  • amoxicillin/clavulanate
  • cloxacillin flecainide
  • azathioprine
  • cyclophosphamide
  • flurazepam
  • captopril
  • cyclosporine
  • flutamide
  • carbamazepine
  • danazol
  • glyburide
  • carbimazole
  • diazepam
  • gold
  • cephalosporins
  • disopyramide
  • griseofulvin
  • chlordiazepoxide
  • enalapril
  • enalapril
  • haloperidol
  • ketoconazole
  • norethandrolone
  • sulfonamides
  • mercaptopurine
  • oral contraceptives
  • tamoxifen
  • methyltestosterone
  • oxacillin
  • thiabendazole
  • nifedipine
  • penicillamine
  • tolbutamide
  • nitrofurantoin
  • phenothiazines
  • tricyclic antidepressants
  • nonsteroidal
  • phenytoin troleandomycin
  • anti-inflammatory drugs
  • propoxyphene
  • verapamil

Drugs that may cause LIVER GRANULOMAS (chronic inflammatory nodules)

  • allopurinol
  • gold
  • phenytoin
  • aspirin
  • hydralazine
  • procainamide
  • carbamazepine
  • isoniazid
  • quinidine
  • chlorpromazine
  • isoniazid
  • quinidine
  • chlorpromazine
  • nitrofurantoin
  • sulfonamides
  • diltiazem
  • penicillin
  • tolbutamide
  • disopyramide
  • phenylbutazone

Drugs that may cause CHRONIC LIVER DISEASE

Drugs that may cause active chronic hepatitis

  • acetaminophen (chronic use, large doses)
  • dantrolene
  • methyldopa
  • isoniazid
  • nitrofurantoin

Drugs that may cause liver cirrhosis or fibrosis (scarring)

  • methotrexate
  • terbinafine HCI (Lamisil, Sporanox)
  • nicotinic acid

Drugs that may cause chronic cholestasis (resembling primary biliary cirrhosis)

  • chlorpromazine/valproic acid (combination)
  • imipramine
  • thiabendazole
  • phenothiazines
  • tolbutamide
  • chlorpropamide/erythro-mycin (combination)
  • phenytoin

Drugs that may cause LIVER TUMORS (benign and malignant)

  • anabolic steroids
  • oral contraceptives
  • thorotrast
  • danazol
  • testosterone

Drugs that may cause DAMAGE TO LIVER BLOOD VESSELS

  • adriamycin
  • dacarbazine
  • thioquanine
  • anabolic steroids
  • mercaptopurine
  • vincristine
  • azathioprine
  • methotrexate
  • vitamin A (excessive doses)
  • carmustine
  • mitomycin
  • cyclophosphamide/cyclo-sporine (combination)
  • oral contraceptives

Lyric and Wyck’s Hepatitis C Story and The Lost Book Remedies

Lyric and Wycks Hepatitis C Story

Hi, we are Dennie and Vivien, we live in Akron, Ohio. We both have Hepatitis C and this is our story.

I, Vivien, am writing this in the first person, but I write for both of us.

We have a somewhat unique perspective because we are not only heppers, but we each LIVE with a hepper, so we see both sides of the situation.

My husband and I met in 1972. Dennie was recently divorced and I was having problems with my marriage. He was the father of two boys, I was the mother of three boys.

We worked together in a bar and became good friends. This was a period of transition for both of us and we indulged in some heavy partying together. We drank and used drugs recreationally.

We also were involved in a “group tattooing” session with several of our partying friends.

During this period of time, my first husband was killed suddenly in an auto accident and his grief stricken parents abducted my children. With no money or resources, I was unable to find them and get them back for some time. These events increased my use of drugs and alcohol as a way of dealing with my losses.

After about a year of partying, we both became noticeably yellow and I was admitted to a hospital with severe abdominal pains. I was diagnosed as having Hepatitis B. Not being terribly bright at that time, I insisted on being released to go back to my partying. I had several bouts of severe pain after this and I went to the emergency room twice for treatment.

I was told that there was NO evidence of me having had Hepatitis B, and I was given a tranquilizer and an antacid and then sent home. Dennie had milder symptoms, but we both were quite sick for a while. We gradually began to feel better, chalked it up to partying too much and went on about our business.

After a couple years of living together, we were married in 1975. We had fought to find my sons and eventually managed to regain custody of them. Our daughter was born in 1976 and we obtained custody of Dennis’ boys. This gave us six children to care for and we settled down to raise our family. We continued to party on an occasional weekend basis only, and concentrated on making a good life for our children.

The children grew up fast and we watched them gradually move out and start families of their own. Dennie had gone back to his original occupation as a truck driver, both local and long distance. Life was fairly good for us. One day Dennie became nearly paralyzed at work. He was found to have cervical disc disease and arthritis. He was no longer able to pass the required physical for his employment. He was put on massive doses of progressively stronger pain killers. Our life began to crumble at this point, but our love for each other grew stronger.

I had suffered from fatigue for years, and had been referred to endless physicians and psychiatrists with no improvement. The medications they prescribed for me nearly caused me to have a nervous breakdown and I became more and more depressed over my inability to feel well. I finally gave up on receiving any help from that source. I learned to live with it and tried to offset the symptoms with diet pills. Self medication had become a way of life for me.

In March of 1996, I went to the local clinic for a mild case of bronchitis and routine blood work was done. I received the call a few days later, my liver enzymes were a little high and they wanted to do a follow up test, probably nothing to worry about. The second round of tests included a liver profile, and I received the news a few days later. The doctor told me over the phone that I was negative for antibodies to Hepatitis B, but did show antibodies for Hepatitis C, formerly known as Non- A, Non- B Hepatitis. He suggested that Dennie be tested too. He was found to be positive also. I was in shock and then in denial.

We both received letters from the Health Department with info on communicable diseases. I was told by the doctor that I should not kiss my grandchildren. This information of course was false, but it just goes to show how little the doctors knew at this point.

Life went on, I was in denial and refused to think about it. During this period, Dennie had a mild heart attack, but suffered no serious damage. On January 2, 1997, I had a major heart attack. I survived against all odds and I am fine now, with minimal damage, just a metal stent in my artery. But this event pushed me into reassessing my life and where it was going. We began to seek out information and advice. The addition of a computer to our lives was the motivating factor and we began to learn more about our illness, enabling us to make informed decisions and interact with others.

We started on a basic regimen of vitamins, milk thistle, gingko biloba, siberian ginseng and coenzyme Q10. We both had biopsies in the summer of 1998. My biopsy result was focal minimal early cirrhosis and non-specific severe chronic inflammation associated with acute focal inflammation, portal cells, clinically Hepatitis C.

Dennie’s biopsy showed adequate liver with fatty change associated with fibrosis with psuedolobules. No evidence of bile stasis. Extensive fibrosis noted. Fatty change with cirrhosis.

We embarked on a study at the University Hospital of Cleveland involving the use of Infergen on treatment naive patients. We were both considered to be unsuitable for combo treatment because of our heart conditions. Dennie started first and was put on 9mcg. 3 x weekly.

After three months, I was put on the same dose of Infergen and Dennie was upped to 15 mcg. At the end of another three months, we were both discontinued as non-responders. Our enzymes had stayed about the same, and my platelets and WBC were steadily dropping to alarming levels.

Our viral loads had more than TRIPLED during the course of the treatment. The Infergen treatment was well tolerated by both of us, but unfortunately, it didn’t work for us. We were genotyped but they were unable to determine a type for either of us. The theory is that the virus has probably mutated too badly to be classified.

About six months later, Dennie attempted the daily dosing Infergen in a study conducted at University Hospital. He ended up in the 9 mcg daily group, but when he showed no response, they again raised the dose to 15 mcg. His viral load shot up again and there was no improvement in his ALT and AST. He was discontinued again as a non-responder.

With our gastro’s approval, we continued to use the vitamins and herbs. Since going off treatment and doing nothing but the herbs and vitamins, we had liver enzymes in the high normal range for the first time in years.

Dennie has been on medications for pain for some time now. He originally was put on them to alleviate his arthritis pain, but now it’s needed for all his health problems. In addition to advanced cirrhosis, he suffers from cervical disc disease, arthritis, fibromyalgia, bursitis, and emphysema. He is treated by a pain management clinic and takes Percocets, Somas, and wears a morphine patch constantly.

I am beginning to notice more fatigue and increased problems with fluid retention. Our bloodwork results are gradually becoming worse.

Unless a miracle happens and a medication becomes available that will work for us, we both face the ultimate decision of transplant.

Dennie has made the decision NOT to have one for many reasons, the main one being that his overall health is so poor that he wouldn’t be considered a good candidate for transplant anyway. I, of course, would rather NOT have to have one, but am not ruling the possibility out at this time.

Now for the real issue, how do two people with hepatitis C get along? We have had to make major adjustments in our lifestyles but have done it so gradually that we didn’t notice it happening. We help each other, when one has a bad day, it seems like the other rallies. It is hard to get things done, but there are definite advantages to living with someone who truly knows what you are going through. There are times when we just pass each other and nod. There are times when we hold each other tight and cry together.

There are good times and bad times, but we are always together and our lives are intertwined in every way and using the lost book of remedies has helped us a ton.

There are times when we get on each other’s last nerve too. Sometimes it’s difficult to look at each other. It’s like seeing a reflection in a bad mirror…the pain, confusion, sadness and regret are there in the other’s eyes.

There is also the feeling of complete understanding and acceptance though. There are no feelings of anger or resentment towards each other…we got this together, we are in this together and we will stick it out.

At this time, we are resting, waiting to see what will come along, and trying to take care of ourselves to the best of our ability. We are sharing our story in the hope that someone will be able to learn something from us, just as we have learned from others.

We have not given up the fight, we are just searching for new weapons and with the Dr. Apelian’s lost book of herbal remedies in our disposal, we’ll win the war.

Please feel free to contact us if you need to talk to someone who understands. Contact Vivien (Lyric) by email at contact us page.

August Hepatitis Fest in Bennett Spring State Park in Missouri (The Lost Book of Remedies Opening)

Hepfest in missouri

Here is a very basic list of information. It should answer most questions.

If not contact Phatress, email addy phatress@hotmail.com,or lil3feathers, contact us, and we should be able to answer any questions you may have.

This would mean if you plan on staying from Friday until Monday, you need to plan on making sleeping arrangements for 3 nights.

Pavilion B has been reserved for Friday and Sunday with a copy of the lost book of herbal remedies. We will also be able to use it for part of Saturday since the people who have already reserved it are celebrating a 50th wedding anniversary and don’t plan on being there the whole length of the day.

They have graciously told Phatress that we may have it for the remainder of the day on Saturday after they have finished with their celebration.

The BASIC campsites, for those who are planning on pitching tents and camping out for the weekend and wish to reserve a campsite are $8.50(a one time fee for each campsite that is reserved in advance), plus $8.00 per night. In addition…if any changes are made to reservations a $5.00 fee will be added. If not reserved the price for a basic campsite is $8.00 per night.

Following are charges for campsites that have a few added “luxuries”: $14.00 a night for a campsite with electric hookups, $15.00 a night for a campsite with electric and water hookups, $17.00 a night for a campsite with electric, water, and sewer hookups.

The maximum number of persons on a campsite is six, unless the unit is indivisible. Also, there are limits on the number of sleeping units you may place on each campsite.

Check with park staff  for current camping policies.

A camping day is from 3 p.m. until 3 p.m. the following day. You must arrive within the first camping day reserved or your reserved site will be released.

You must vacate the reservable campsite on your last camping day by 2 p.m. All campsite fees are to be paid directly to the campgrounds main office. Pay by credit card, debit card backed by major credit cards, check, or money order.

There are currently 3 cabins reserved. Check out times for the cabins is 11:00 a.m. Each cabin will sleep 6 people. The price per night for each cabin is $150.00, which breaks down to $25.00 per person each night.

They do not guarantee specific rooms, so what cabins we get will determine what kind of bed arrangement there is in each one holding the lost book of remedies on their hands.

All three cabins reserved are together.

The cabins will be on a first come first served basis, so those who send in their money will be the first to be guaranteed a bed.

We are keeping a list of monies received to ensure that this happens.

There will be one “planned” meal each day, in the evening. Each person is responsible for bringing any food and drinks they will need throughout the day.

Phatress had to pay $70.00 out of her pocket to reserve the pavilion for the two days we can have it. I have sent her $25.00 to help pay her back for that out of pocket expense.

Anyone who can afford to pitch in a few dollars to pay her back the remaining $45.00 would be much appreciated.

Those dollar bills add up quick! In addition to bringing all food and drink I feel I will need over the weekend I am bringing a few extra things to add into the evening meal kitty.

Am going to bring a pound or two of hamburger, and a few packages of brats or hotdogs.

It would be great if anyone who can would bring a little bit extra, like maybe bags of chips, hot dog and/or  hamburger buns, things like that.

We really feel that too much more planning would be a pain in the rear to carry out.

Other than the things listed above, that HAVE to be taken care of, we feel the only other plan we all need to arrive at the hepfest with is to plan on having FUN!!!!

Seems like the best times are things that just happen….to many plans seem to be a setup to fail.

Any other ideas would be gladly taken into consideration so feel free to put forth any suggestions you might have.

Hope this clarifies things a little bit, and we will add more info as it becomes available, or if necessary.